Sm ELISA Test kit





Sm ELISA Test kit Intended Use
Sm ELISA test kit is a semi-quantitative immunoassay for the detection of IgG antibodies to Sm in human sera. The results of this assay may aid in the diagnosis and treatment follow up of autoimmune connective tissue disorders.





Sm ELISA Kit Components:
• Microplate: 96 wells coated with inactivated antigen
• HRP Conjugated goat anti-human IgG (Fc chain specific)
• Sample Diluent
• Positive Control
• Negative Control
• Calibrator
• Wash Buffer (10X)
• TMB Substrate Solution
• Stop Solution (1M H2SO4, 0.7M HCI)





Method Principle
This Diagnostic Automation/ Cortez Diagnostics Inc. Human Sm ELISA test kit is designed to detect IgG class antibodies to Sm in human sera. Wells of microplate are sensitized by passive absorption with immobilized antigens. The test procedure involves three incubation steps. For further details please refer to complete instructions manual supplied with the product.





Background Information
The Anti-Smith (Anti-Sm) autoantibody is one of a family of characteristic autoantibodies which are very specific marker for Systemic lupus erythematosus (SLE). Approximately 99% of individuals with anti-Sm antibodies have the disease, but about 30% of people with SLE have the antibodies. The Sm autoantigens are the small nuclear ribonucleoprotein (snRNP) common core proteins.




For more information about ELISA Kits, Rapid Tests, IFA Kits, CLIA Test Kits, or Serology tests, please see our website home page, or contact our Customer Service Representative at 818-591-3030.