Semi-Quantitative - Positive, Negative and Cut-off
Sample
10ul serum
Specificity
96%
Sensitivity
100%
Total Time
~60 min
Shelf Life
12 Months from the manufacturing date
Description
Jo-1 ELISA Test kit
Jo-1 ELISA Test kit Intended Use
Jo-1 ELISA test kit is a semi-quantitative immunoassay for the detection of IgG antibodies to Jo-1 in human sera. The results of this autoantibody profile may aid in the diagnosis and treatment of autoimmune connective tissue disorders.
Method Principle
This Diagnostic Automation/ Cortez Diagnostics Inc. Human Jo-1 ELISA test kit is designed to detect IgG class antibodies to Jo-1 in human sera. Wells of microplate are sensitized by passive absorption with MPO antigen. The test procedure involves three incubation steps. For further details please refer to complete instructions manual supplied with the product.
Background Information
The Jo-1 autoantibody is one of a family of characteristic autoantibodies seen in myositis patients. They are all specifically found in patients with myositis, and are all associated with a high incidence of accompanying interstitial lung disease. Generally, these autoantibodies to a number of nuclear constituents have proven to be useful in the diagnosis of various connective tissue diseases.
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