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Name Epstein Barr Virus Early Antigen (EA) IgG ELISA kit
Price $410.00
Category NameInfectious Disease ELISA kits
MethodELISA: Enzyme Linked Immunosorbent Assay
PrincipleELISA - Indirect; Antigen Coated Plate
Detection RangeQualitative - Positive, Negative and Cut-off
Total Time90min
Shelf Life12-18months from the manufacturing date

Item #:                    1415-2   Quantity:               



EBV ELISA Test kit

EBV ELISA Test kit Intended Use
EBV-EA IgG ELISA test kit is designed for the qualitative detection of IgG antibodies to Epstein-Barr Virus (EBV) Early Antigen (EA) in human sera. This test kit is intended to aid in the diagnosis of infectious mononucleosis (IM) when used with other EBV serologies.

EBV IgG ELISA Kit Components:
• Microplate: 96 wells coated with inactivated EBV-EA antigen
• HPR-Enzyme Conjugate Goat anti-human IgG
• Sample Diluent
• Calibrator
• Positive Control
• Negative Control
• Wash Buffer (10X)
• Stop Solution (1M H2SO4, 0.7 HCl)

Method Principle
This Diagnostic Automation/ Cortez Diagnostics Inc. Human EBV-EA ELISA test system is designed to detect IgG class antibodies to Epstein-Barr virus Early Antigen in human sera. Wells of plastic microplate strips are sensitized by passive absorption with EBV-EA antigen. The test procedure involves three incubation steps. For further details please refer to complete instructions manual supplied with the product.

Background Information
Epstein-Barr Virus (EBV) is a ubiquitous human virus which causes infectious mononucleosis (IM), a self-limiting lymphoproliferative disease. By adulthood virtually everyone has been infected with and has developed immunity to the virus. In underdeveloped countries, seroconversion to the virus takes place in early childhood and is usually asymptomatic. In more affluent countries, primary EBV infections are often delayed until adolescence or later, and manifest as IM in about 50% of this age group. Following seroconversion, whether symptomatic or not, EBV establishes a chronic, latent infection in B lymphocytes which may last for life. EBV early antigen (EA) consists of two components; diffuse (D), and restricted (R). Antibodies to EA may appear transiently for up to three months or longer during the acute phase of IM in 85 % of patients. The antibody response to EA in 1M patients is usually to the D component, whereas silent seroconverison to EBV in children may produce antibodies to the R components. The ELISA procedure, may be a sensitive and reliable method for detection of antibodies to EBV antigens. The ELISA procedure allows an objective determination of antibody status based on a single dilution of the test specimen and is suitable for screening large numbers of patient samples.

For more information about ELISA Kits, Rapid Tests, IFA Kits, CLIA Test Kits, or Serology tests, please see our website home page, or contact our Customer Service Representative at 818-591-3030.